PON2 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | IHC:1:100-1:1000; WB:1:500-1:3000 |
| Reactivity | Bovine), Human, Mouse (Predicted: Dog, Pig, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1 and 295 of PON2 (Uniprot ID#Q15165) |
| Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Concentration | lot specific |
| Purification | Purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 39 kDa |
| Gene Name | paraoxonase 2 |
| Database Link | |
| Background | This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq |
| Synonyms | A-esterase 2; aromatic esterase 2; arylesterase 2; paraoxonase 2; paraoxonase nirs; serum aryldialkylphosphatase 2; serum paraoxonase |
| Note | Seq homology of immunogen across species: Dog (92%), Pig (93%), Rat (90%), Bovine (92%) |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.