PHKA1 Rabbit Polyclonal Antibody
CAT#: TA308404
Rabbit Polyclonal antibody to PHKA1 (phosphorylase kinase, alpha 1 (muscle))
USD 200.00
USD 867.00
USD 665.00
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000 |
Reactivities | Human (Predicted: Mouse, Rat) |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fragment corresponding to a region within amino acids 828 and 1062 of PHKA1 (Uniprot ID#P46020) |
Formulation | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 137 kDa |
Gene Name | phosphorylase kinase regulatory subunit alpha 1 |
Database Link | |
Background | The PHKA1 gene encodes the alpha subunit of muscle phosphorylase kinase (EC 2.7.1.38), a key regulatory enzyme of glycogen metabolism. Phosphorylase kinase consists of 4 copies of an alpha-beta-gamma-delta tetramer. The alpha, beta (PHKB; MIM 172490), and gamma (PHKG1; MIM 172470 and PHKG2; MIM 172471) subunits have several isoforms; the delta subunit is calmodulin (CALM1; MIM 114180). PHKA2 (MIM 306000) encodes the alpha subunit of liver-specific phosphorylase kinase and is also located on the X chromosome. [supplied by OMIM] |
Synonyms | PHKA |
Note | Seq homology of immunogen across species: Mouse (96%), Rat (95%) |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Calcium signaling pathway, Insulin signaling pathway |
Documents
Product Manuals |
FAQs |
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