Junctional Adhesion Molecule 2 (JAM2) Rabbit Polyclonal Antibody

CAT#: TA308335

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Rabbit Polyclonal antibody to JAM-B (junctional adhesion molecule 2)


Product Datasheet for 'TA308335'


USD 415.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Applications IHC, WB
Recommended Dilution IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 294 of JAM-B (Uniprot ID#P57087)
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml
Purification Purified by antigen-affinity chromatography.
Predicted Protein Size 33 kDa
Gene Name junctional adhesion molecule 2
Background Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq]
Synonyms C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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