MRPL3 Rabbit Polyclonal Antibody

CAT#: TA308301

Rabbit polyclonal antibody to MRPL3 (mitochondrial ribosomal protein L3)

Product Images

Sample (30 ug of whole cell lysate). A:293T. B:A431. 12% SDS PAGE. TA308301 diluted at 1:500

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human (Predicted: Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 286 and 348 of MRPL3 (Uniprot ID#P09001)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 39 kDa
• Gene Name: mitochondrial ribosomal protein L3
• Database Link:
  NP_009139
  Entrez Gene 11222 Human
  UniProt ID P09001
• Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q. [provided by RefSeq]
• Synonyms: COXPD9; MRL3; RPML3
• Note: Seq homology of immunogen across species: Bovine (100%)

Reference Data

• Protein Families: Druggable Genome