ICAM2 Rabbit Polyclonal Antibody

CAT#: TA308279

Rabbit Polyclonal antibody to ICAM2 (intercellular adhesion molecule 2)

Product Images

Sample (30 ug whole cell lysate). A:HeLa S3. 12% SDS PAGE. TA308279 diluted at 1:1000

• 

  Immunohistochemical analysis of paraffin-embedded breast cancer, using ICAM2 (TA308279) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Monkey)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 189 of ICAM2 (Uniprot ID#P13598)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 31 kDa
• Gene Name: intercellular adhesion molecule 2
• Database Link:
  NP_001093259
  Entrez Gene 574158 MonkeyEntrez Gene 3384 Human
  UniProt ID P13598
• Background: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
• Synonyms: CD102
• Note: Seq homology of immunogen across species: Monkey (85%)

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity