RASA3 Rabbit Polyclonal Antibody

SKU TA308271

Rabbit polyclonal antibody to RASA3 (RAS p21 protein activator 3)

Product Data

• Application: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivity: Bovine), Chicken, Human (Predicted: Mouse, Xenopus
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 746 and 834 of RASA3 (Uniprot ID#Q14644)
• Buffer: 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 96 kDa
• Gene Name: RAS p21 protein activator 3
• Database Link:
  NP_031394
  Q14644
• Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq]
• Synonyms: GAP1IP4BP; GAPIII
• Note: Seq homology of immunogen across species: Mouse (87%), Xenopus laevis (93%), Chicken (100%), Bovine (87%)

Reference Data