PLAAT4 Rabbit Polyclonal Antibody
SKU
TA308191
Rabbit polyclonal antibody to RARRES3 (retinoic acid receptor responder (tazarotene induced) 3)
$665.00
2 Weeks*
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB:1:500-1:3000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 69 and 164 of RARRES3 (Uniprot ID#Q9UL19) |
| Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Concentration | lot specific |
| Purification | Purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 18 kDa |
| Gene Name | retinoic acid receptor responder 3 |
| Database Link | |
| Background | Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. provided by RefSeq |
| Synonyms | 2-3; HRASLS4; HRSL4; PLA1; RIG1; TIG3 |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
RARRES3 suppressed metastasis through suppression of MTDH to regulate epithelial-mesenchymal transition in colorectal cancer
Wang, Wang, Hu et al
Am J Cancer Res (2015) 5 (6), 1988-99
Wang, Wang, Hu et al
Am J Cancer Res (2015) 5 (6), 1988-99
AI Summary: OriGene contributed to this study by providing the lentiviral shRNA vector pGFP-C-shLenti-RARRES3 (TL320510) and shRNA scramble control, which were used to knock down RARRES3 expression in colorectal cancer cell lines to investigate its role in metastasis suppression.
Snippet: and penicillin/streptomycin in a 5% CO 2 humidified incubator at 37°C. For knockdown experiments, lentiviral short hairpin RNA (shRNA) vector pGFP-C-shLenti- RARRES3 (TL 320510) and shRNA scramble control were all purchased from Origene (Origene Technologies ... Cite SaveSaving
Up-regulation of PFTK1 is significantly associated with metastasis and poor prognosis in pancreatic ductal adenocarcinoma
Li, Xiao, Sun et al
International Journal of Clinical and Experiemental Medicine (2016) 9 (6), 9455-9460
Li, Xiao, Sun et al
International Journal of Clinical and Experiemental Medicine (2016) 9 (6), 9455-9460
Snippet: Immunohistochemical stain- ing was carried out using heat-induced epito- pe retrieval, an avidin-biotin complex method. The rabbit anti-PFTK1 antibody (TA 308191, Origene Technologies, Inc, USA) was diluted with 1:100. ... Cite SaveSaving
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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