RAPGEF5 Rabbit Polyclonal Antibody

SKU TA308169

Rabbit polyclonal antibody to RAPGEF5 (Rap guanine nucleotide exchange factor (GEF) 5)

Product Data

• Application: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivity: Human (Predicted: Monkey)
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 179 of Human RAPGEF5
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 85 kDa
• Gene Name: Rap guanine nucleotide exchange factor 5
• Database Link:
  NP_036426
  Q92565
• Background: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]). [supplied by OMIM]
• Synonyms: GFR; MR-GEF; REPAC
• Note: Seq homology of immunogen across species: Monkey (98%)

Reference Data