PRPS2 Rabbit Polyclonal Antibody
$665.00
In Stock*
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000 |
| Reactivity | Bovine, Human (Predicted: Mouse, Rat, X. tropicalis), Xenopus |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 243 of PRPS2 (Uniprot ID#P11908) |
| Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Purification | Purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 35 kDa |
| Gene Name | phosphoribosyl pyrophosphate synthetase 2 |
| Database Link | |
| Synonyms | PRSII |
| Note | Seq homology of immunogen across species: Mouse (97%), Rat (97%), Xenopus laevis (96%), Bovine (97%), Xenopus tropicalis (97%) |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Pentose phosphate pathway, Purine metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
HuR is a post-transcriptional regulator of core metabolic enzymes in pancreatic cancer
Burkhart, Pineda, Chand et al
RNA Biol (2013) 10 (8), 1312-23 DOI: 10.4161/rna.25274
Burkhart, Pineda, Chand et al
RNA Biol (2013) 10 (8), 1312-23 DOI: 10.4161/rna.25274
Cited by 66
AI Summary: In this study, OriGene’s HuR shRNA (Cat# TL311089) and HuR overexpression plasmid (Cat# SC119295) were used to manipulate HuR expression levels in pancreatic cancer cell lines, enabling the authors to demonstrate HuR’s critical role in regulating core metabolic enzymes and cell survival under glucose deprivation.
Showing 1-1 of 1 papers.
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