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MTGR1 (CBFA2T2) Rabbit Polyclonal Antibody

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SKU
TA308048
Rabbit polyclonal antibody to CBFA2T2 (core-binding factor, runt domain, alpha subunit 2; translocated to, 2)
Size:
100 ul
Conjugation:
Unconjugated
  $665.00
In Stock*
Bulk/Customize

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View other "MTGR1 or NM_005093" antibodies

Specifications
Specifications
Product Data
Application IF, WB
Recommended Dilution ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivity Chicken, Human (Predicted: Mouse, Rat)
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 401 and 604 of CBFA2T2 (Uniprot ID#O43439)
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 67 kDa
Gene Name CBFA2/RUNX1 translocation partner 2
Database Link
Background In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. provided by RefSeq
Synonyms EHT; MTGR1; p85; ZMYND3
Note Seq homology of immunogen across species: Mouse (95%), Chicken (80%), Rat (95%)
Reference Data
Protein Categories Intracellular Proteins
Protein Families Transcription Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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