NPEPPS Rabbit Polyclonal Antibody
$665.00
2 Weeks*
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | ICC/IF:1:100-1:1000; WB:1:500-1:3000 |
| Reactivity | Bovine, Human, Mouse (Predicted: Rat, X. tropicalis) |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 328 and 648 of NPEPPS (Uniprot ID#P55786) |
| Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
| Concentration | lot specific |
| Purification | Purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 99 kDa |
| Gene Name | aminopeptidase puromycin sensitive |
| Database Link | |
| Background | This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. provided by RefSeq |
| Synonyms | AAP-S; MP100; PSA |
| Note | Seq homology of immunogen across species: Rat (97%), Bovine (96%), Xenopus tropicalis (85%) |
| Reference Data | |
| Protein Categories | Enzyme: Peptidases, Intracellular Proteins |
| Protein Families | Druggable Genome, Protease |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Regulation of volume-regulated anion channels alters sensitivity to platinum chemotherapy
Feldman, Mohapatra, Jones et al
Sci Adv (2024) 10 (50), eadr9364 DOI: 10.1126/sciadv.adr9364
Feldman, Mohapatra, Jones et al
Sci Adv (2024) 10 (50), eadr9364 DOI: 10.1126/sciadv.adr9364
Cited by 9
AI Summary: OriGene’s rabbit polyclonal NPEPPS antibody (TA308014) was used to detect NPEPPS protein in experiments investigating the interaction between NPEPPS and volume-regulated anion channels, contributing to the study’s findings on cisplatin resistance mechanisms.
Snippet: itive control. Anti-FLAG pull-down was performed for FLAG nonexpressing BCa cell line for the negative control. NPEPPS and LRRC8A have been probed using the rabbit polyclonal NPEPPS antibody (1:1000;Origene, TA308014), rabbit IgG polyclonal LRRC8A antibody (1:1000, LSBio, LS-C290818 and LS-B16989), and rabbit IgG polyclonal LRRC8D antibody (1:1000, Sino Biological, 104245-T32). For fractionated m
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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