RSRC1 Rabbit Polyclonal Antibody

CAT#: TA306925

Rabbit Polyclonal RSRC1 Antibody

Product Images

Western blot analysis of RSRC1 in HepG2 cell lysate with RSRC1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of RSRC1 in rat liver tissue with RSRC1 antibody at 5 ug/mL.

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  Immunofluorescence of RSRC1 in rat liver tissue with RSRC1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: RSRC1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RSRC1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: arginine/serine-rich coiled-coil 1
• Database Link:
  NP_057709
  Entrez Gene 66880 MouseEntrez Gene 361956 RatEntrez Gene 51319 Human
  UniProt ID Q96IZ7
• Background: The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker.
• Synonyms: BM-011; SFRS21; SRrp53