PLPP6 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | WB: 1 ug/mL, IF: 20 ug/mL |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | PPAPDC2 antibody was raised against a 13 amino acid peptide from near the carboxy terminus human PPAPDC2. |
| Buffer | PBS containing 0.02% sodium azide. |
| Concentration | 1ug/ul |
| Purification | Affinity chromatography purified via peptide column |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | phospholipid phosphatase 6 |
| Database Link | |
| Background | PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase. |
| Synonyms | bA6J24.6; PDP1; PPAPDC2; PSDP |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Role of Phosphatidic Acid Phosphatase Domain Containing 2 (PPAPDC2) In Squalestatin 1-Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes
Pant, Kocarek
Drug Metab. Dispos. (2015)
Pant, Kocarek
Drug Metab. Dispos. (2015)
Cited by 2
AI Summary: OriGene products contributed to this study by providing four plasmids expressing 29-mer shRNAs targeting rat PPAPDC2 and a non-targeting shRNA plasmid (TR30012), as well as a rabbit polyclonal antibody against PPAPDC2, which were used to manipulate and detect PPAPDC2 expression in primary cultured rat hepatocytes.
Snippet: Four plasmids expressing 29-mer shRNAs targeting rat PPAPDC2 and a non-targeting shRNA plasmid (TR30012) were purchased from Origene Technologies (Rockville, MD). ... rabbit polyclonal antibody (Origene Technologies). Additional details are presented in ... Cite SaveSaving
Showing 1-1 of 1 papers.
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