MARVELD1 Rabbit Polyclonal Antibody

CAT#: TA306880

Rabbit Polyclonal MARVELD1 Antibody

Product Images

Western blot analysis of MARVELD1 in mouse heart tissue lysate with MARVELD1 antibody at (A) 1 and (B) 2 ug/ml.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MARVELD1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human MARVELD1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: MARVEL domain containing 1
• Database Link:
  NP_113672
  Entrez Gene 277010 MouseEntrez Gene 309375 RatEntrez Gene 83742 Human
  UniProt ID Q9BSK0
• Background: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2’-deoxycytidine restores MARVELD1 expression (1,3), suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
• Synonyms: bA548K23.8; GB14; MARVD1; MRVLDC1