CDC42 Chicken Polyclonal Antibody

SKU TA306749

Chicken Polyclonal CDC42 Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL
• Reactivity: Human, Mouse, Rat
• Antibody Host: Chicken
• Isotype: IgY
• Clonality: Polyclonal
• Immunogen: CDC42 antibody was raised against a 17 amino acid peptide near the amino terminus of human CDC42.
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: cell division cycle 42
• Database Link:
  NP_001782
  P60953
• Background: CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.
• Synonyms: CDC42Hs; G25K

Reference Data