LRFN2 Rabbit Polyclonal Antibody

CAT#: TA306739

Rabbit Polyclonal LRFN2 Antibody

Product Images

Western blot analysis of LRFN2 in rat brain lysate with LRFN2 antibody at (A) 1 and (B) 2ug/ml.

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  Western blot analysis of LRFN2 expression in mouse brain tissue lysate with LRFN2 antibody at 1ug/ml.

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  Immunohistochemistry of LRFN2 in mouse brain tissue with LRFN2 antibody at 2.5ug/ml.

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  Immunofluorescence of LRFN2 in mouse brain tissue with LRFN2 antibody at 20ug/ml.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: LRFN2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human LRFN2. The immunogen is located within amino acids 700 - 750 of LRFN2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: leucine rich repeat and fibronectin type III domain containing 2
• Database Link:
  NP_065788
  Entrez Gene 70530 MouseEntrez Gene 316205 RatEntrez Gene 57497 Human
  UniProt ID Q9ULH4
• Background: LRFN2 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN2 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.
• Synonyms: FIGLER2; KIAA1246; SALM1

Reference Data

• Protein Families: Transmembrane