GNPDA2 Rabbit Polyclonal Antibody

CAT#: TA306736

Rabbit Polyclonal GNPDA2 Antibody

Product Images

Western blot analysis of GNPDA2 in human kidney lysate with GNPDA2 antibody at 1 ug/mL.

• 

  Immunocytochemistry of GNPDA2 in 293 cells with GNPDA2 antibody at 4 ug/mL.

• 

  Immunofluorescence of GNPDA2 in mouse kidney tissue with GNPDA2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, ICC:4 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: GNPDA2 antibody was raised against an 8 amino acid peptide near the carboxy terminus of human GNPDA2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: glucosamine-6-phosphate deaminase 2
• Database Link:
  NP_612208
  Entrez Gene 67980 MouseEntrez Gene 132789 Human
  UniProt ID Q8TDQ7
• Background: Glucosamine-6-phosphate deaminase (GNPDA) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered, and is closer in structure and activity to the E. coli enzyme than GNPDA1. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2. GNPDA2 antibody is predicted to not cross-react with GNPDA1.
• Synonyms: GNP2; SB52

Reference Data

• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Metabolic pathways