MED4 Rabbit Polyclonal Antibody

SKU TA306618

Rabbit Polyclonal MED4 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 0.5 ug/mL, ICC: 10 ug/mL
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MED4 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human MED4.
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: mediator complex subunit 4
• Database Link:
  NP_054885
  Q9NPJ6
• Background: The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment. At least three isoforms of MED4 are known to exist; this antibody only recognizes the largest isoform.
• Synonyms: ARC36; DRIP36; HSPC126; TRAP36; VDRIP

Reference Data

• Protein Families: Druggable Genome, Transcription Factors