Interferon beta (IFNB1) Rabbit Polyclonal Antibody

SKU
TA306437
Rabbit Polyclonal IFN-beta Antibody
  $640.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 5 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen IFN-beta antibody was raised against a 17 amino acid synthetic peptide from near the center of human IFN-b. The immunogen is located within amino acids 110 - 160 of IFN-beta.
Buffer PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name interferon beta 1
Database Link
Background Type I Interferons (IFN-a/b) are produced primarily in response to viral infection by “Natural IFN-producing cells" (IPCs) as part of the host immune response and can also inhibit the development of tumors. IFN-b binding by its receptor results in the activation of the tyrosine kinases Jak1 and Tyk2 and phosphorylation of members of the STAT family of transcription factors, leading to the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-b. IFN-b is currently used clinically for treatment of tumors, infections and multiple sclerosis.
Synonyms IFB; IFF; IFNB
Reference Data
Protein Categories Chemokines, Cytokines, Secreated Proteins
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Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling
Jie, Luo, Chen et al
Oncotarget (2017) 8 (62), 105615-105629 DOI: 10.18632/oncotarget.22350
Snippet: β-actin rabbit pAb (1:2000) was from Bioworld (MN, USA). IFN-β rabbit pAb (1:500) was from OriGene Technology (MD, USA). p-IRF3 rabbit mAb (1:1000), NF-κB p65 rabbit mAb (1:2000) and TNF-α rabbit pAb (1:2000) were provided by Cell Signaling Technology (MA
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New insights into the effects and mechanism of a classic traditional Chinese medicinal formula on influenza prevention
Chen, Jie, Tang et al
Phytomedicine (2017) 27, 52-62 DOI: 10.1016/j.phymed.2017.02.004
Cited by 39
AI Summary: OriGene products, specifically the anti-MAVS antibody (Cat# TA343575) and anti-IFITM3 antibody (Cat# TA500647), were used in this study to detect protein expression levels and elucidate the mechanism by which KangBingDu (KBD) enhances antiviral responses against influenza.
New insights into the effects and mechanism of a classic traditional Chinese medicinal formula on influenza prevention
Chen, Jie, Tang et al
Phytomedicine (2017) 27, 52
AI Summary: In this study, OriGene's interferon-β (IFN-β) antibody (TA306437) was used to investigate the molecular mechanisms underlying the traditional Chinese medicinal formula's effects on influenza prevention.
Snippet: provided by Cell Signaling Technology Inc. (Boston, USA). Antibody against interferon-β (IFN-β) (TA306437) was bought from OriGene Technology (MD, USA). Antibodies against interferon inducible transmembrane 3 (IFITM3 ... Cite SaveSaving
Showing 1-3 of 3 papers.
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