TRPC3 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 1 - 2 ug/mL, ICC: 10 ug/mL |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | TRPC3 antibody was raised against a 14 amino acid peptide from near the amino terminus of human TRPC3. |
| Buffer | PBS containing 0.02% sodium azide. |
| Purification | Affinity chromatography purified via peptide column |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | transient receptor potential cation channel subfamily C member 3 |
| Database Link | |
| Background | The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the “canonical TRP” (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors (2). TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels. |
| Synonyms | SCA41; TRP3 |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Canonical transient receptor potential 3 channel triggers vascular endothelial growth factor-induced intracellular Ca2+ oscillations in endothelial progenitor cells isolated from umbilical cord blood
Dragoni, Laforenza, Bonetti et al
Stem Cells Dev (2013) 22 (19), 2561-80 DOI: 10.1089/scd.2013.0032
Dragoni, Laforenza, Bonetti et al
Stem Cells Dev (2013) 22 (19), 2561-80 DOI: 10.1089/scd.2013.0032
Cited by 79
Showing 1-1 of 1 papers.
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