BCL2L10 Rabbit Polyclonal Antibody

CAT#: TA306134

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Rabbit Polyclonal Bcl-B Antibody


 Product Datasheet for 'TA306134'

USD 415.00


Availability*
5 Days

Size
    • 100 ug


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Specifications

Product Data
Applications IF, WB
Recommend Dilution WB: 1 ug/mL, ICC: 10 ug/mL
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Bcl-B antibody was raised against a 16 amino acid peptide from near the amino terminus of human Bcl-B.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Gene Name BCL2 like 10
Background Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications.
Synonyms BCL-B; Boo; Diva; bcl2-L-10
Reference Data
Protein Families Druggable Genome, Transmembrane
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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