TTC5 Rabbit Polyclonal Antibody

CAT#: TA306112

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Rabbit Polyclonal TTC5 Antibody



USD 528.00


Availability*
5 Days

Size
    • 100 ug


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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 0.5 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen TTC5 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TTC5.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Immunoaffinity purified IgG
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name tetratricopeptide repeat domain 5
Background Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
Synonyms Strap
Reference Data
Frequently bought together (2)
Transient overexpression lysate of tetratricopeptide repeat domain 5 (TTC5)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.