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Apoptosis repressor with CARD (NOL3) Rabbit Polyclonal Antibody

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SKU
TA305985
Rabbit Polyclonal ARC Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $640.00
5 Days*
Bulk/Customize

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View other "Apoptosis repressor with CARD or NM_003946" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, IHC: 5 ug/mL
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen ARC antibody was raised against a peptide corresponding to amino acids 191 to 208 of human origin.
Buffer PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name nucleolar protein 3
Database Link
Background Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). ARC interacts with caspase-2 and –8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue (1).
Synonyms ARC; FCM; MYP; NOP; NOP30
Reference Data
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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