LINGO1 Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 1:1000, IHC: 1:10~50 |
Reactivity | Chicken, Human (Predicted: Mouse, Monkey) |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This LINGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of human LINGO1. |
Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration | lot specific |
Purification | This antibody is purified through a protein G column, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 69876 Da |
Gene Name | leucine rich repeat and Ig domain containing 1 |
Database Link | |
Background | LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. |
Synonyms | LERN1; LRRN6A; UNQ201 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
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