DNMT3A Rabbit Polyclonal Antibody

SKU
TA301633
Rabbit Polyclonal Antibody against DNMT3a
  $610.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application ICC/IF, IHC, IP, WB
Recommended Dilution Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence: 1:500, Immunoprecipitation: 1:10-1:500, Western Blot: 1:1000, Immunohistochemistry-Paraffin: 1:200
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen This antibody was raised against amino acids 10-118 of the human DNMT3a protein.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name DNA (cytosine-5-)-methyltransferase 3 alpha
Database Link
Background Inactivation of tumor suppressor genes is a key component of the development of all common forms of human cancers. Aberrant methylation may contribute to many of the changes, both physiological and pathological, associated with aging, including tumor development. Hypermethylation of CpG island-containing promoters is associated with the inactivation of genes important to tumor angiogenesis and progression. DNA methytransferase (DNMT3a) is necessary for the maintenance of the methylation process.
Synonyms DNMT3A2; M.HsaIIIA; TBRS
Reference Data
Protein Categories Cancer: Haematopoietic and Lymphoid, Cardiovascular diseases, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome
Protein Pathways Cysteine and methionine metabolism, Metabolic pathways
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