MAT2A Rabbit Polyclonal Antibody

SKU TA301493

Rabbit Polyclonal Antibody against MAT2 alpha

Product Data

• Application: ICC/IF, IHC, IP, Simple Western, WB
• Recommended Dilution: Simple Western, Western Blot: 1.0 ug/ml, Immunocytochemistry/ Immunofluorescence: 1:2000, Immunohistochemistry: 1:200, Immunohistochemistry-Paraffin: 1:200, Immunoprecipitation
• Reactivity: Bovine, Human, Monkey, Orang-Utan (Does not react with: Mouse), Rat, Zebrafish
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide made to an N terminal portion of the human protein (within residues 1-100). [Swiss-Prot# P31153]
• Buffer: PBS, 30% glycerol and 0.1% sodium azide
• Concentration: lot specific
• Purification: peptide affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: methionine adenosyltransferase 2A
• Database Link:
  NP_005902
  P31153
• Background: MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.
• Synonyms: MATA2; MATII; SAMS2

Reference Data

• Protein Pathways: Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism