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ADGRE1 (N-term, extracell. dom.) Rabbit Polyclonal Antibody

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SKU
SP4660P
ADGRE1 (N-term, extracell. dom.) rabbit polyclonal antibody, Aff - Purified
Size:
50 ug
Conjugation:
Unconjugated
  $550.00
3 Weeks*
Bulk/Customize

View other "ADGRE1 or NP_001965.3" antibodies

Specifications
Specifications
Product Data
Application ELISA, IHC
Recommended Dilution ELISA.
Immunohistochemistry on Paraffin Sections: 18 - 36 µg/ml.
Reactivity Human
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Synthetic 19 amino acid peptide from N-terminal extracellular domain of human EMR1
Specificity Reacts with N-terminal extracellular domain of EGF-Like Module-Containing Mucin-Like Receptor 1 (EMR1) (family: GPCR, subfamily: Orphan-B).
Buffer PBS containing 0.09% Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name adhesion G protein-coupled receptor E1
Database Link
Background EGF-Like Module Containing Mucin-Like Hormone Receptor-Like Sequence 1 (EMR1) is characterized as an Orphan-B GPCR with an unknown ligand. The C-terminus contains seven hydrophobic segments, characteristic of a G protein-coupled receptor. The N-terminus of EMR1 has 6 EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties.
F4/80 is a monoclonal antibody that recognizes a murine macrophage- restricted cell surface glycoprotein whose amino acid sequence has been determined to be the EMR1 gene. Therefore, the data from this antibody can be used to derive gene expression of mouse EMR1.
EMR1 has been reported to be expressed in human peripheral blood mononuclear cells, monocytes, and hematopoietic and solid tumor-derived cell lines. ESTs have been isolated from human normal spleen and mixed liver/spleen libraries and from human kidney, colon, brain, and bone marrow cancer libraries.
Reference Data
Protein Categories GPCR, Intracellular Proteins, Membrane Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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