TAC1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, IHC |
|---|---|
| Recommended Dilution | Immunofluorescence: 1/200-1/400 (IF Microscopy using FITC with overnight incubation at 2-8°C). Immunohistochemistry on Paraffin Embedded and Frozen tissues: 1/400-1/800 (using PAP). Positive Control: Formalin-fixed paraffin sections of Rat colon. |
| Reactivity | Fish, Human, Porcine, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Substance K / Neurokinin A (Peninsula) conjugated to BSA |
| Specificity | This antibody reacts with Substance K / Neurokinin A. Absoprtion with 10-100 µg Substance K per ml diluted antiserum abolishes the staining, while Substance P does not. |
| Buffer | State: Serum State: Lyophilized undiluted Serum. |
| Reconstitution Method | Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.09% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Prior to reconstitution store at 2-8°C. Following reconstitution store the antibody at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | tachykinin precursor 1 |
| Database Link | |
| Background | Neurokinin A/Substance K represents a member of the tachykinin family of peptides. Neurokinin A, which arises by cleavage of the substance P precursor, occurs in neurons in the central and peripheral nervous systems, and is particularly numerous in the gastrointestinal tract. The biological actions of neurokinin A are similar to those of substance P, and include vasodilation and stimulation of smooth muscle contraction. |
| Synonyms | TAC1, NKA, NKNA, TAC2, Protachykinin-1, Substance K, Neuromedin L |
| Reference Data | |
| Protein Categories | Growth Factors, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
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