Lyve1 Rabbit Polyclonal Antibody

CAT#: DP3513

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Lyve1 rabbit polyclonal antibody, Purified



USD 418.00


Availability*
2 Weeks

Size
    • 200 ug


Specifications

Product Data
Applications ELISA, FC, IF, IHC, WB
Recommended Dilution ELISA (1-15 µg/ml).
Western blot (1-5 µg/ml).
FACS analysis (3-10 µg/ml).
Immunofluorescence.
Immunohistochemistry on Frozen Sections
(1-5 µg/ml).
For formalin-fixed, paraffin-embedded sections use the immunogen affinity purified antibody Cat.-No DP3513P.
Reactivity Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Highly pure recombinant Mouse soluble LYVE-1 (Ala24-Gly228) produced in insect cells (Cat.-No DA3524).
This recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis).
Specificity This antibody detetcs Mouse and Rat Lyve-1. 
This antibody is not reactive with Human LYVE-1.
Formulation PBS, pH 7.2 without preservatives or stabilizers
State: Purified
State: Lyophilized purified IgG fraction
Reconstitution Method Restore in sterile water to a concentration of 0.1-1.0 mg/ml.
Purification Protein G Chromatography (+his tag depletetion)
Conjugation Unconjugated
Storage The lyophilized IgG is stable at 2-8°C for one month and at -20°C for longer.
When reconstituted the antibody is stable for at least six weeks at 2-8°C.
For longer store in aliquots at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212- esidue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE- molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymphspecific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Synonyms LYVE1, CRSBP-1, CRSBP1, HAR, XLKD1
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.