OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Lyve1 Rabbit Polyclonal Antibody

Be the first to review this product
SKU
DP3513
Lyve1 rabbit polyclonal antibody, Purified
Size:
200 ug 100 ug
Conjugation:
Unconjugated
  $510.00
2 Weeks*
Bulk/Customize

View other "Lyve1 or NP_444477.2" antibodies

Specifications
Specifications
Product Data
Application ELISA, FC, IF, IHC, WB
Recommended Dilution ELISA (1-15 µg/ml).
Western blot (1-5 µg/ml).
FACS analysis (3-10 µg/ml).
Immunofluorescence.
Immunohistochemistry on Frozen Sections (1-5 µg/ml).
For formalin-fixed, paraffin-embedded sections use the immunogen affinity purified antibody Cat.-No DP3513P.
Reactivity Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Highly pure recombinant Mouse soluble LYVE-1 (Ala24-Gly228) produced in insect cells (Cat.-No DA3524).
This recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis).
Specificity This antibody detetcs Mouse and Rat Lyve-1.
This antibody is not reactive with Human LYVE-1.
Buffer PBS, pH 7.2 without preservatives or stabilizers
State: Purified
State: Lyophilized purified IgG fraction
Reconstitution Method Restore in sterile water to a concentration of 0.1-1.0 mg/ml.
Purification Protein G Chromatography (+his tag depletetion)
Conjugation Unconjugated
Storage The lyophilized IgG is stable at 2-8°C for one month and at -20°C for longer.
When reconstituted the antibody is stable for at least six weeks at 2-8°C.
For longer store in aliquots at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Gene Name lymphatic vessel endothelial hyaluronan receptor 1
Database Link
Background LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212- esidue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE- molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymphspecific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Synonyms LYVE1, CRSBP-1, CRSBP1, HAR, XLKD1
Reference Data
Protein Categories Membrane Proteins
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function
Rangel-Moreno, de la Luz Garcia-Hernandez, Ramos-Payan et al
Radiat Res (2015) 184 (4), 352-66 DOI: 10.1667/RR14047.1
AI Summary: In this study, OriGene products, specifically the anti-Bcl6 antibody (Cat# TA500495) and anti-Ki67 antibody (Cat# TA500648), were used for immunohistochemical analysis to assess germinal center formation and cellular proliferation in secondary lymphoid organs, contributing to the evaluation of long-term immune dysfunction following neonatal total body gamma irradiation.
FigureFigure
Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis
Heishi, Hosaka, Suzuki et al
Am J Pathol (2010) 176 (4), 1950-8 DOI: 10.2353/ajpath.2010.090829
Cited by 92
AI Summary: In this study, OriGene’s human vasohibin1 cDNA (RC210375) was used to generate adenoviruses for gene delivery, enabling the authors to investigate and demonstrate vasohibin1’s inhibitory effects on lymphangiogenesis and lymph node metastasis in cancer models.
FigureFigureFigure
Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo
Conrad, Niess, Huss et al
Circulation (2009) 119 (2), 281-9 DOI: 10.1161/CIRCULATIONAHA.108.793208
AI Summary: In this study, OriGene products, specifically the Prox-1 (TA328632) and podoplanin (TA328299) antibodies, were used to characterize the lymphatic differentiation of mesenchymal stem cells by detecting the expression of key lymphatic markers.
Showing 1-3 of 3 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products