TrkA (NTRK1) Mouse Monoclonal Antibody [Clone ID: OTI5B6]
SKU
CF806413
Carrier-free (BSA/glycerol-free) NTRK1 mouse monoclonal antibody, clone OTI5B6 (formerly 5B6)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI5B6 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 440-796 of human NTRK1(NP_002520) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 87.3 kDa |
| Gene Name | neurotrophic receptor tyrosine kinase 1 |
| Database Link | |
| Background | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. provided by RefSeq, Jul 2008 |
| Synonyms | MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA |
| Reference Data | |
| Protein Categories | Cancer: Brain and CNS, Cancer: Endocrine, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Apoptosis, Endocytosis, MAPK signaling pathway, Neurotrophin signaling pathway, Pathways in cancer, Thyroid cancer |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI5B6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA806413 | NTRK1 mouse monoclonal antibody, clone OTI5B6 (formerly 5B6) | 100 ul |
$447.00
|
|
| TA806413AM | NTRK1 mouse monoclonal antibody, clone OTI5B6 (formerly 5B6), Biotinylated | 100 ul |
$509.00
|
|
| TA806413BM | NTRK1 mouse monoclonal antibody, clone OTI5B6 (formerly 5B6), HRP conjugated | 100 ul |
$509.00
|
|
| TA806413S | NTRK1 mouse monoclonal antibody, clone OTI5B6 (formerly 5B6) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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