CAMLG Mouse Monoclonal Antibody [Clone ID: OTI1A3]
Specifications
| Product Data | |
| Clone Name | OTI1A3 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CAMLG(NP_001736) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 32.8 kDa |
| Gene Name | calcium modulating ligand |
| Database Link | |
| Background | The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. provided by RefSeq |
| Synonyms | CAML |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1A3" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA504329 | CAMLG mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) | 100 ul |
$447.00
|
|
| TA504329AM | CAMLG mouse monoclonal antibody, clone OTI1A3 (formerly 1A3), Biotinylated | 100 ul |
$509.00
|
|
| TA504329BM | CAMLG mouse monoclonal antibody, clone OTI1A3 (formerly 1A3), HRP conjugated | 100 ul |
$509.00
|
|
| TA504329S | CAMLG mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) | 30 ul |
$200.00
|
|
Citations
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