CAMLG Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A3]
Specifications
| Product Data | |
| Clone Name | OTI1A3 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CAMLG(NP_001736) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Biotin |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 32.8 kDa |
| Gene Name | calcium modulating ligand |
| Database Link | |
| Background | The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. provided by RefSeq |
| Synonyms | CAML |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI1A3" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF504329 | Carrier-free (BSA/glycerol-free) CAMLG mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) | 100 ug |
$620.00
|
|
| TA504329 | CAMLG mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) | 100 ul |
$447.00
|
|
| TA504329BM | CAMLG mouse monoclonal antibody, clone OTI1A3 (formerly 1A3), HRP conjugated | 100 ul |
$509.00
|
|
| TA504329S | CAMLG mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) | 30 ul |
$200.00
|
|
Citations
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