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CDX2 Mouse Monoclonal Antibody [Clone ID: OTI1A3]

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SKU
CF500251
Carrier-free (BSA/glycerol-free) CDX2 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "CDX2 or NM_001265" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1A3
Application IF, WB
Recommended Dilution WB 1:1000
Reactivity Dog, Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 33.5 kDa
Gene Name caudal type homeobox 2
Database Link
Background The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730)and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
Synonyms CDX-3; CDX2/AS; CDX3
Reference Data
Protein Categories Cancer: Gastrointestinal, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors
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Other "OTI1A3" antibodies (4)
SKU Description Size Price
TA500251 Anti-CDX2 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) 100 ul
$447.00
TA500251AM Anti-CDX2 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3), Biotinylated 100 ul
$509.00
TA500251BM Anti-CDX2 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3), HRP conjugated 100 ul
$509.00
TA500251S Anti-CDX2 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) 30 ul
$200.00

file-alt Citations

Neurons generated from carcinoma stem cells support cancer progression
Lu, Fan, Shangguan et al
Signal Transduct Target Ther (2017) 2, 16036 DOI: 10.1038/sigtrans.2016.36
AI Summary: In this study, OriGene's CDX2 antibody (TA500251) was used as a primary antibody to help identify and characterize cancer stem cell-derived neurons involved in tumor neurogenesis and cancer progression.
Snippet: The primary antibodies used were: Beta-3-tublin (Chicken, Novus, Littleton, CO, USA nb100-1612), NuMA (Rabbit, Abcam, Cambridge, MA, USA ab84680), NuMA (Goat, Santa-Cruz, Dallas, TX, USA sc-18557), MAP2 (Rabbit, Santa-Cruz sc-20172), CDX2 (Mouse, Origene, Beijing, China TA500251), CK20 (Rabbit, Abcam ab-76126), TH (Chicken, Abnova, Taipei City, China PAB29094),
FigureFigureFigure
Showing 1-1 of 1 papers.
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