CDX2 Mouse Monoclonal Antibody [Clone ID: OTI1A3]

SKU TA500251

Anti-CDX2 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3)

Product Data

• Clone Name: OTI1A3
• Application: IF, WB
• Recommended Dilution: WB 1:1000
• Reactivity: Dog, Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 33.5 kDa
• Gene Name: caudal type homeobox 2
• Database Link:
  NP_001256
  Q99626
• Background: The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730)and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
• Synonyms: CDX-3; CDX2/AS; CDX3

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors