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c-Myc (MYC) Mouse Monoclonal Antibody [Clone ID: OTI1A6]

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SKU
CF500002
Carrier-free (BSA/glycerol-free) c-Myc mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "c-Myc or NM_002467" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1A6
Application FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human Myc (NP_002458) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 50.4 kDa
Gene Name MYC proto-oncogene, bHLH transcription factor
Database Link
Background c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Synonyms bHLHe39; c-Myc; MRTL; MYCC
Reference Data
Protein Categories Cancer: Brain and CNS, Cancer: Gastrointestinal, Cancer: Gynecologic, Cancer: Haematopoietic and Lymphoid, Cancer: Head and Neck, Cancer: Lung, Cancer: Sarcoma, Cancer: Skin, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Stem cell relevant signaling - Wnt Signaling pathway, Transcription Factors
Protein Pathways Acute myeloid leukemia, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Pathways in cancer, Small cell lung cancer, TGF-beta signaling pathway, Thyroid cancer, Wnt signaling pathway
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Other "OTI1A6" antibodies (6)
SKU Description Size Price
TA500002 c-Myc (c-Myc ) mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) 100 ul
$447.00
TA500002AM c-Myc mouse monoclonal antibody, clone 1A6, Biotinylated 100 ul
$509.00
TA500002BM c-Myc mouse monoclonal antibody, clone 1A6, HRP conjugated 100 ul
$509.00
TA500002S c-Myc (c-Myc ) mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) 30 ul
$200.00
TA600497 purified MYC mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
$458.00
TA700496 MYC biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays 50 ug
$494.00

file-alt Citations

Vasopressin-to-Oxytocin Receptor Crosstalk in the Preoptic Area Underlying Parental Behaviors in Male Mice
Inada, Hagihara, Yaguchi et al
bioRxiv (2024)
Cited by 2
Snippet: For the immunohistochemistry, the following reagents were used for primary antibodies: anti-GFP (GFP-1010;Aves Labs;1:500), anti-RFP (5f8;Chromotek;1:500), and anti-mCherry (AB0040-200;OriGene;1:500)
IHC
Optimizing rice grain size by attenuating phosphorylation-triggered functional impairment of a chromatin modifier ternary complex
Shen, Ma, Bai et al
Developmental Cell (2024) 59 (4), 448-464.e8 DOI: 10.1016/j.devcel.2023.12.013
Cited by 16
AI Summary: OriGene products, including the mouse monoclonal anti-c-Myc antibody (Cat# TA500002) and the mouse monoclonal anti-eGFP antibody (Cat# TA150052), were used in this study to detect tagged proteins and analyze the molecular mechanisms regulating rice grain size.
Snippet: Mouse monoclonal anti-c-Myc ORIGENE Cat# TA500002;RRID: AB_2148582 Mouse monoclonal anti-GFP TransGen Biotech Cat# HT801;RRID: AB_2922385 Mouse monoclonal anti-eGFP ORIGENE Cat# TA150052;RRID: AB_2622260
Control of grain size in rice by TGW3 phosphorylation of OsIAA10 through potentiation of OsIAA10-OsARF4-mediated auxin signaling
Ma, Shen, Bai et al
Cell Rep (2023) 42 (3), 112187 DOI: 10.1016/j.celrep.2023.112187
Cited by 48
AI Summary: OriGene’s Mouse monoclonal anti-c-Myc antibody (Cat# TA500002) was used in this study to detect c-Myc-tagged proteins, facilitating the analysis of protein interactions and modifications involved in auxin signaling and grain size regulation in rice.
Snippet: Mouse monoclonal anti-c-Myc ORIGENE Cat#TA500002
Microglial TREM2 Mitigates Inflammatory Responses and Neuronal Apoptosis in Angiotensin II-Induced Hypertension in Middle-Aged Mice
Xu, Du, Jiang et al
Front Aging Neurosci (2021) 13, 716917 DOI: 10.3389/fnagi.2021.716917
Cited by 24
AI Summary: In this paper, OriGene’s TREM2 overexpression plasmid (Cat# MR227768) was used to investigate the role of microglial TREM2 in mitigating inflammatory responses and neuronal apoptosis in angiotensin II-induced hypertension in mice.
FigureFigureFigure
Showing 1-4 of 4 papers.
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