Candida albicans Rabbit Polyclonal Antibody
Candida albicans rabbit polyclonal antibody, FITC
|Applications||ELISA, ID, IF, IHC|
|Recommended Dilution||Suitable for use in Double-Diffusion and CIE, direct IFA, ELISA and Immunohistochemistry.
Use neat in gel-precipitin reactions.
|Immunogen||Candida albicans, type A (ATCC#32354)|
|Specificity||Recognizes numerous proteins in a soluble C. albicans extract (IEP).
Has not been absorbed and does cross-react with other yeasts.
Negative against human serum, urine and spinal fluid.
|Formulation||0.01 M PBS, pH 7.2
State: Liquid purified Ig fraction
Stabilizer: 10 mg/ml BSA
Preservative: 0.09% Sodium Azide
Label: Highly purified Isomer I of Fluorescein Isothiocyanate. Care is taken to ensure complete removal of any free fluorescein from the final product.
|Concentration||4-5 mg/ml (OD280 nm, E0.1% = 1.4)|
|Purification||Protein A Chromatography|
|Storage||Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Background||Candida albicans is the most frequently isolated fungal pathogen of humans, affecting immunocompromised patients ranging from premature infants to AIDS sufferers. Systemic infections have an attributed mortality of 30-50%. C. albicans is a diploid organism which has eight sets of homologous chromosomes. It has a genome of approximately 16 Mb (haploid), about 30% greater than S. cerevisiae (baker’s yeast).|
|The use of this Antibodies has been cited in the following citations:|
Rapid and direct quantification of viable Candida species in whole blood by use of immunomagnetic separation and solid-phase cytometry
,Vanhee LM, Meersseman W, Lagrou K, Maertens J, Nelis HJ, Coenye T,
J. Clin. Microbiol. 2018
,PubMed ID 20129966
Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions
,Wagener J, MacCallum DM, Brown GD, Gow NA,
,PubMed ID 28119468