CTRB1 Mouse Monoclonal Antibody [Clone ID: 4E1]

Name: CTRB1 Mouse Monoclonal Antibody [Clone ID: 4E1]
Brand: OEM
SKU: BM293
Price: 645 USD
Availability: InStock

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SKU

BM293

CTRB1 mouse monoclonal antibody, clone 4E1, Purified

Datasheet SDS

<strong>Published customer image:</strong> <br>Mouse anti Human chymotrypsin antibody, clone 4E1 (<strong>BM293</strong>) used for the detection of chymotrypsin in mouse tissues by immunohistochemistry<br><strong>Image caption:</strong><br><strong>Endocrine and exocrine compartments destruction in the pancreas of Pdx1-Cre;LSL-Kras<sup>G12D</sup>;Tif1γ<sup>lox/lox</sup> mice.</strong> Wild-type (A–C') and Pdx1-Cre; LSL-KrasG12D; Tif1γlox/lox (D–L') pancreas sections were stained with HPS (A,D,G,J), immuno-revealed either with an anti-chymotrypsin antibody (B,E,H,K) or an anti-insulin antibody (C,F,I,L and C',F',I',L' that represent the boxed region in C,F,I,L at a higher magnification). For Pdx1-Cre;LSL-Kras<sup>G12D</sup>;Tif1γ<sup>lox/lox</sup> mice, analysis were performed at different ages. Number of mice: 3 weeks, n = 3; 6–13 weeks, n = 5; 18–27 weeks, n = 4. Boxes: Higher magnification. The pictures show one representative mouse for each group.<br><br>From: Vincent DF, Yan K-P, Treilleux I, Gay F, Arfi V, Kaniewsky B, <em>et al</em>. (2009) Inactivation of TIF1γ Cooperates with KrasG12D to Induce Cystic Tumors of the Pancreas.<br><strong><a href="https://www.ncbi.nlm.nih.gov/pubmed/19629168"target="_blank">PLoS Genet 5(7): e1000575</a></strong>.<br>doi: 10.1186/1471-230X-10-19.<br>This image is from an open access article distributed under the terms of the <a href="https://creativecommons.org/licenses/by/4.0/"target="_blank">Creative Commons Attribution License</a>.

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Specifications

Specifications
Product Data
Clone Name	4E1
Application	ELISA, IF, IHC, WB
Recommended Dilution	ELISA. Western Blot. Immunofluorescence. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections.
Reactivity	Human, Mouse, Rat
Antibody Host	Mouse
Isotype	IgG3
Clonality	Monoclonal
Immunogen	Purified Human pancreatic Chymotrypsin.
Specificity	This antibody is specific for Chymotrypsin and does not react with Trypsin.
Buffer	PBS, pH 7.2 containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Shipping	Blue Ice
Gene Name	chymotrypsinogen B1
Database Link	P17538
Background	Chymotrypsin is a 239 amino acid ~30 kD protease with an additional 13 amino acid propeptide region and a 16 amino acid signal peptide. Variations in the CTRC gene has been associated with susceptibility to hereditary, pancreatitis, a disease characterized by pancreatic inflammation and destruction of the parenchyma. Human chymotrypsin-C, also known as chymotrypsin or caldecrin.
Synonyms	CTRB1, CTRB, Chymotrypsinogen B
Reference Data
Protein Categories	Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins

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Documents

Product Manuals
Goat anti-Mouse IgG [H&L] Western Blotting Luminol Kit
FAQs
Antibody and Western Standard
SDS
SDS for BM293

Resources

Antibody Resources
Product Overview Video: TrueMAB Video Tutorial: Video Tutorial: Antibody specificity and Knockout(KO) lysates Western Blot Protocol IHC Protocol IF Protocol FACS Protocol Immunoprecipitation (IP) Protocol IP protocol with magnetic beads

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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CTRB1 Mouse Monoclonal Antibody [Clone ID: 4E1]

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