SRY Rabbit Polyclonal Antibody
Rabbit Polyclonal Anti-SRY Antibody, Purified
Product Datasheet for 'AP60006PU-L'
|Immunogen||Highly pure recombinant human bovine SRY (Met1 - Tyr229) derived derived from E. coli (Cat.-No. AR60006PU-N)|
|Purification||Protein A chromatography|
|Gene Name||sex determining region Y|
|Background||The ?Sex determining region of Y-Gen¡± (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex.|
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