MDC1 pSer513 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | Immunohistochemistry on paraffin sections: 1:50~1:100. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1 (KLH-conjugated) |
| Specificity | The antibody detects endogenous levels of MDC1 only when phosphorylated at serine 513. |
| Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Affinity chromatography using epitope-specific peptide |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 226 kDa |
| Gene Name | mediator of DNA damage checkpoint 1 |
| Database Link | |
| Background | The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint. |
| Synonyms | MDC1, KIAA0170, NFBD1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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