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BLK pTyr501 Rabbit Polyclonal Antibody

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SKU
AP55751PU-N
BLK pTyr501 rabbit polyclonal antibody, Aff - Purified
Size:
100 ul 50 ul
Conjugation:
Unconjugated
  $430.00
2 Weeks*
Bulk/Customize

View other "BLK or NP_001706.2" antibodies

Specifications
Specifications
Product Data
Application IHC
Recommended Dilution Immunohistochemistry on paraffin sections: 1:50~1:100.
Reactivity Human, Mouse
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK (KLH-conjugated)
Specificity The antibody detects endogenous levels of BLK only when phosphorylated at tyrosine 501.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 57 kDa
Gene Name BLK proto-oncogene, Src family tyrosine kinase
Database Link
Background Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor.
Synonyms B lymphocyte kinase, p55-BLK, p55BLK
Reference Data
Protein Categories Diabetes, Enzyme: Kinases, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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