HPSE2 (C-term) Rabbit Polyclonal Antibody

SKU AP52095PU-N

HPSE2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/100-1/500. ; Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 450-480 amino acids from the C-terminal region of human Heparanase-2 / HPA2
• Specificity: This antibody recognizes Human Heparanase-2 / HPA2 (C-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: heparanase 2 (inactive)
• Database Link:
  Q8WWQ2
• Background:
  Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.
• Synonyms: HPSE2
• Note: Molecular Weight: 66596 Da

Reference Data

• Protein Pathways: Glycosaminoglycan degradation, Metabolic pathways