AASS (C-term) Rabbit Polyclonal Antibody

CAT#: AP50013PU-N

AASS (C-term) rabbit polyclonal antibody, Purified

Product Images

AASS Antibody (C-term) western blot analysis in K562 cell line lysates (35 ug/lane).This demonstrates the AASS antibody detected the AASS protein (arrow).

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  AASS Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/50 - 1/100.
  Flow Cytometry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 812-841 amino acids from the C-terminal region of human AASS.
• Specificity: This antibody reacts to AASS.
• Formulation: PBS with 0.09% (W/V) sodium azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: aminoadipate-semialdehyde synthase
• Database Link:
  Entrez Gene 10157 Human
  UniProt ID Q9UDR5
• Background: This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
• Synonyms: LKR/SDH
• Note: Molecular Weight: 102132 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysine biosynthesis, Lysine degradation, Metabolic pathways