AOC2 Rabbit Polyclonal Antibody

CAT#: AP43408PU-N

AOC2 rabbit polyclonal antibody, Aff - Purified

Product Images

Human Lung; WB Suggested Anti-AOC2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Lung; AOC2 antibody - middle region (AP43408PU-N) in Human Lung cells using Western Blot

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blotting (0.2 - 1 µg/ml).

• Reactivities: Bovine, Canine, Chicken, Human, Mouse, Rat, Zebrafish, African clawed frog
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide directed towards the middle region of human AOC2
• Formulation: State: Aff - Purified
  State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Purified using peptide immunoaffinity column
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: amine oxidase, copper containing 2
• Database Link:
  Entrez Gene 314 Human
  UniProt ID O75106
• Background: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.
• Synonyms: DAO2; RAO; SSAO

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: beta-Alanine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism