BCL2 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA |
|---|---|
| Recommended Dilution | ELISA: React with the synthetic Bcl-2 peptide coated on ELISA plate. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | A synthetic peptide derived from human Bcl-2, conjugated with KLH |
| Specificity | This antibody recognizes the synthetic Bcl-2 peptide. |
| Buffer | 0.01M PBS, pH 7.4 State: Azide Free State: Lyophilized Ig fraction |
| Reconstitution Method | Restore with Double distilled water to adjust the final concentration to 1.00 mg/ml. |
| Purification | Protein G affinity purified |
| Conjugation | Unconjugated |
| Storage | Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | B-cell CLL/lymphoma 2 |
| Database Link | |
| Background | Bcl2 is a 25kDa inner mitochondrial membrane protein with anti-apoptotic function. It is believed that Bcl-2 suppresses apoptosis by inhibiting mitochondrial cytochrome C release, blocking caspase cascade and regulating mitochondrial calcium homeostasis. Bcl- 2 is identified from the study of B-cell lymphoma. About 90% of follicular lymphoma is caused by Bcl-2 overexpression resulted from the translocation of Bcl-2 gene from chromosome 18 to the immunoglobulin heavy chain enhancer on chromosome 14. Bcl-2 is also involved with other malignancies such as melanoma, breast cancer, prostate cancer and lung cancer. |
| Synonyms | BCL2, Bcl-2 alpha |
| Reference Data | |
| Protein Categories | Cancer: Gynecologic, Cancer: Haematopoietic and Lymphoid, Cancer: Head and Neck, Cancer: Lung, Cancer: Sarcoma, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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