EIF2S2 pSer2 Rabbit Polyclonal Antibody

SKU AP26039PU-N

EIF2S2 pSer2 rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution: Western blot: 1:500 - 1:1000.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide sequence around phosphorylation site of serine 2 derived from eIF2β.
• Specificity: This antibody detects endogenous levels of eIF2β only when phosphorylated at serine 2.
• Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol; State: Aff - Purified; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity-chromatography using epitope-specific peptide
• Conjugation: Unconjugated
• Storage: Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: eukaryotic translation initiation factor 2 subunit beta
• Database Link:
  P20042
• Background: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
• Synonyms: Eukaryotic translation initiation factor 2 subunit 2, eIF-2-beta, eIF2-beta
• Note: Molecular weight: 38 kDa

Reference Data