PP2A-alpha (PPP2CA) (N-term) Rabbit Polyclonal Antibody

CAT#: AP15290PU-N

PP2A-alpha (PPP2CA) (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis: PPP2CA/PPP2CB antibody staining of A2058 cell line lysates at 35 ug.

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  Immunohistochemistry: PPP2CA/PPP2CB antibody staining of Formalin-Fixed Paraffin-Embedded Human cancer tissue followed by peroxidase conjugated secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Peptide ELISA: 1/1,000.
  Western blotting: 1/1000.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide peptide between 1~30 amino acids from the N-terminal region of Human PPP2CA/B.
• Specificity: This antibody recognizes PPP2CA/PPP2CB.
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: protein phosphatase 2 catalytic subunit alpha
• Database Link:
  Entrez Gene 5515 Human
  UniProt ID P67775
• Background: PPP2CA/B represents the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
• Synonyms: Protein Phospatase 2A, PP2A-alpha, Replication protein C, PP2A-beta

Reference Data

• Protein Families: Druggable Genome, Phosphatase, Transcription Factors
• Protein Pathways: Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway