MAP3K12 (C-term) Rabbit Polyclonal Antibody

SKU AP13892PU-N

MAP3K12 (C-term) rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA 1:1,000.; Western blot 1:100 - 1:500.; Immunohistochemistry 1:50 - 1:100.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ZPK.
• Specificity: This antibody detects MAP3K12 at C-term.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Purified; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: mitogen-activated protein kinase kinase kinase 12
• Database Link:
  Q12852
• Background: ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
• Synonyms: Mixed lineage kinase, MAPK-upstream kinase
• Note: Molecular weight: 93188 Da

Reference Data