CDC25A Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/50 - 1/100. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | Ig |
| Clonality | Polyclonal |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S78 of human CDC25A. |
| Specificity | This antibody reacts to CDC25A at Ser78. |
| Buffer | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Protein A column, followed by peptide affinity purification |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | cell division cycle 25A |
| Database Link | |
| Background | CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. |
| Synonyms | CDC-25A |
| Reference Data | |
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