ABCB4 Rabbit Polyclonal Antibody

SKU AP13075PU-N

ABCB4 rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Peptide ELISA.; Western blotting: 1/1000.; Immunohistochemistry: 1/50-1/100.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 624-654 amino acids from the Central region of Human ABCB4.
• Specificity: This antibody recognizes ABCB4/MDR3 (Center)
• Buffer: PBS with 0.09% (W/V) Sodium Azide as preservative; State: Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: ATP binding cassette subfamily B member 4
• Database Link:
  P21439
• Background: The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
• Synonyms: Multidrug resistance protein 3, P-glycoprotein 3, PGY3

Reference Data